Praziquantel

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Humblefish

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Excellent advice by @Big G :love:

The only thing I can think to add is perform a freshwater dip if you suspect flukes inside the eyes:

This will dislodge the worms in the eyes before you dose Prazipro, which causes them to spasm (before dropping off) and could possibly damage the fish's eyes.
 

Humblefish

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Can’t find the faces any more?
The faces?? You mean the smilies?

Screen Shot 2020-11-07 at 7.19.56 PM.jpg
 

JRFReef65

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:D They were three rows deep. They don’t show up like they did before :unsure: Oh where would I find attachment 8864. Not everyone understands how the elderly are still learning every day!
 
Hey @Humblefish and @Big G sorry this is gonna be a long post but want to make sure you have background.

I have a 60 cube with the following fish
Clown, firefish, cardinal, clown goby, orchid dottyback.
I have some corals in the tank, and some of my live rock has feather dusters.

All fish have been through copper QT, and all have been in the tank about 6 months. I am concerned I may have flukes because the fish have never been treated for them, but I have no proof.
I had a yellow corris wrasse get popeye and die a week later months ago(and was flashing prior to dying). My Flasher wrasse died as well (I think he was scratching prior to dying).
My firefish flashes on the sand once in a while (but he may just be showing off).
Clown a couple times has been shaking his head and flashing in sand. But only a couple days in the last month.

It’s too hard for me to catch the fish because the rock is cemented together and they are quicker than me.

I would like to do 2 doses of prazipro just to make sure I don’t have flukes before I add any more fish or coral. I put all fish through copper quarantine and will make sure to treat fish for flukes now too. All corals and inverts are QTed in a fishless tank.

Does this seem like an appropriate plan to treat with prazipro? I used the calculator and one dose day 1 and 2nd dose on 7th day.

I would take out rock with feather dusters for a while.
What is time period for fluke eggs to die on the rock not treated with prazi?
 
Just wanted to update in this thread.

I am treating all 3 of my tanks with prazipro. 2.5 mg/L. I will do 2 doses 6 days apart per the calculator.

I decided not to take the rock out with featherdusters because I read in some cases they do OK and I wanted to treat my coral quarantine to make sure I don’t have flatworms.

Today is day 2 and my 60 gal cube is doing ok. Corals are ok, fish are all ok, inverts are fine. Featherdusters on the live rock are still out and filtering. Clown was acting funny and quite bothered yesterday but is better today. Firefish only flashed in the sand once today.

10 gallon macro tank with mandarin looks normal.

10 gallon coral quarantine is fine. Interestingly, the one torch I have had problems with since it arrived (never extended and I have done a couple iodine dips) looked better than it ever has today. Maybe the problem with it was some flatworm that I was unaware of.

Please note, I do not have a bunch of bristleworms or flatworms that I was worried about dying off and causing toxin or ammonia issues in the tank.
my experience may not translate to
others tanks.
 

Jposch

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So, with confirmed flukes, after dosing prazi, and especially Fenbendazole, I noticed symptoms intensify, which worms have seizures would do that, but if I am treating prophylactic, and this does no occur, is that a good bet that they didn't have flukes? I still plan to follow with a 2nd treatment, but want to avoid Fenbendazole for the 2nd round if that observation means anything.
 

Humblefish

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So, with confirmed flukes, after dosing prazi, and especially Fenbendazole, I noticed symptoms intensify, which worms have seizures would do that, but if I am treating prophylactic, and this does no occur, is that a good bet that they didn't have flukes? I still plan to follow with a 2nd treatment, but want to avoid Fenbendazole for the 2nd round if that observation means anything.
I really only notice the twitching when a fish is heavily infested. Fish I give a freshwater dip to, which dislodges most of the flukes, don't react much to prazi being dosed in the water. They might scratch one time or something.
 

Jposch

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I really only notice the twitching when a fish is heavily infested. Fish I give a freshwater dip to, which dislodges most of the flukes, don't react much to prazi being dosed in the water. They might scratch one time or something.
Thanks. I was just curious if that was of any useful.induction or not. The only time I had seen that obvious reaction was the batch if fish that had gill flukes that made it through h202 dip, 3 rounds of general cure, and finally Fenbendazole took care of them.
 

Humblefish

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Made this edit to the sticky:

There is also a higher concentration bath dosage that you can use with straight praziquantel powder + DMSO, which may be useful for eliminating so-called prazi resistant flukes. You give the fish a 6-8 hour bath in a large glass container or food grade plastic bucket @ 7.5 mg/L (or 28 mg/gal). It is very important to both temperature control and heavily aerate the water throughout the bath. If possible, transfer the fish into a new/clean QT after the bath to avoid possible reinfection from fluke eggs in the old tank. And remember to do a second bath + transfer into a clean QT about a week later to deal with any leftover fluke eggs on the fish itself.
 

anthonys_aqua

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For the 7.5 mg/L bath? I personally would only use powder praziquantel (dissolved with DMSO) for this. Or in the UK they have a product called “Sera Tremazol” which is already at the 7.5 mg/L prazi dosage.
Sorry I meant for a food soak, I currently have prazi and metroplex but if general cure is better I can get that
 

Humblefish

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Sorry I meant for a food soak, I currently have prazi and metroplex but if general cure is better I can get that
General Cure contains both prazi + metro in one medication, so it's just easier to food soak that than both medications separately. Just be sure to shake the packet really well (or roll the bulk canister) to help ensure both ingredients are more evenly distributed.
 
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