SO now....

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Humblefish

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CP not working. Next fish likely to pass will be my adult beautiful queen angel. He has the same “bacterial film” as all the others manifested before passing. This is definitely going to drive me away from the hobby.
I think your only choice is to pull all the fish and treat in a quarantine tank. It sounds like the bacteria in your DT is degrading the Chloroquine faster than redosing can keep up.
 

DexterB

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@Humblefish Would a H2O2 bath help before transfer to QT tank with CP? Or do current fish have open abrasions etc. from bacterial infection where H2O2 might sting/burn fish??
 

Humblefish

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@Humblefish Would a H2O2 bath help before transfer to QT tank with CP? Or do current fish have open abrasions etc. from bacterial infection where H2O2 might sting/burn fish??
A 30 min bath en route to QT would be beneficial unless a fish is showing redness:
 

Flame2hawk

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A 30 min bath en route to QT would be beneficial unless a fish is showing redness:
I think your only choice is to pull all the fish and treat in a quarantine tank. It sounds like the bacteria in your DT is degrading the Chloroquine faster than redosing can keep up.
I dont see how that’s going to work when no one has even been able to diagnose what it is? I’ve been advised to medicate at extra strength to ensure that therapeutic levels have been reached and maintained. Have done that with all medications and no success. Your theory is that bacteria is negating impact of medication. However I’m sure you know and certainly I know many who have been successful treating bacterial and parasitic infections in DT. My theory is we have no idea what they have and thus have not treated appropriately. What is forgotten is that I did take 2 fish out at different times and treated based on suggestions. They both did not survive. That’s why my theory of not having a proper diagnosis and thus treatment is likely correct. Either way as Ive said, setting up a DT for all these fish is just not an option. I’m counting down the days of sadness and getting out of the hobby. I am defeated. There still allot to learn in this hobby as there is no one who has landed on a firm diagnosis which is the problem. So incredibly sad....
 

Flame2hawk

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Have you considered sending a water sample to @AquaBiomics to get a microbiome and eDNA test? That could tell us what’s actually present in your water.
Are you suggesting a water sample post RO filter or water sample from the aquarium or both? I’ve also been dosing with CP for the last 6 days so not sure how that might impact readings. Thx for your thoughts and do let me know.
 

Jessican

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Are you suggesting a water sample post RO filter or water sample from the aquarium or both? I’ve also been dosing with CP for the last 6 days so not sure how that might impact readings. Thx for your thoughts and do let me know.
I mean from the aquarium to see what parasite DNA, if any, is present.

@AquaBiomics would meds in the water affect the testing?
 

Flame2hawk

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How are the fish reacting? Seem to be helping?
Overall the fish are lethargic. Most are still eating. Exception is Yellow Tang who doesn’t look bad but has stopped eating. The Queen angel has always been the one that is acting sick with lots of scratching, some skin discoloration and heavier breathing but still eating. TYhe scribble angel looks a bit better and has never stopped eating. Other fish lethargic but eating. I guess the queen is scratching ever so slightly less but still flashing and having sudden bursts. So overall after 7 days at double dose then suggested by protocol #2, no water changes at all, I would say very slight improvement. High water volume circulation and oxygen exchange also being used. Due to the bio in tank I decided to double suggested dosage every day and no water changes. I monitor closely and are dosing with Prime. Plan is to go with this regimen for at least 10 days, so 3 more days and stop for some days before doing a water change. Of course if stress manifest itself, I would go ahead with water change earlier. This is all experimental as none of the protocols direct this regimen. Had to try something more aggressive as everything else was not working. I can at least say that I’ve lost no fish in the last 7 days of treatment.
 

Flame2hawk

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I mean from the aquarium to see what parasite DNA, if any, is present.

@AquaBiomics would meds in the water affect the testing?
I’m relatively convinced it is not parasitic but of course sending water sample makes sense IF the CP dosing does not interfere with the results so waiting to hear response form @AquaBiomics. Thanks everyone for your interest and feedback. I’m slightly motivated to keep trying now....thx to you all. Hang in there with me please!
 

Flame2hawk

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Well the (rather expensive) experiment with CP is ending today after 10 days. The Queen angel is still scratching, rubbing and flashing, the yellow tang still isn’t eating and rest of fish look as they did before treatment. Suffice to say we still dont know what they have and certainly have not found the right treatment. Big water change tonight. Still a mystery to all. Will probably send in am water sample to Aquabiomics and give that a shot.....
 

Flame2hawk

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I’m still lost on whats going on with my FOWLR and the fish unfortunately are suffering. @Aquabiomics stated that they cannot diagnose a full range of possible ailments and in any event I would have to wait until symptoms are gone before they could test. I questioned this and the person said would refer to “Eli” who never got back to me. Any way the fish will die one by one as they are all stressed and some are not eating and others very sparingly. The queen angel continues to have a whitish covering/sheen, YT not eating etc. you know the drill. As a reminder all known suggestions have been implemented and in some cases more than once ie Hypo, copper, CP, Prazi, combo of metro/ Furon2/kanoplex, etc etc. nothing has worked. Its not likely to be parasitic although the behaviors say so...scratching,. Flashing, shaking, wrasse consistently cleaning, etc.

So lets re group.....I have fish that act very nervous, hide allot, some eat, others dont, white sheen on angel and on some others, all Very sensitive to light to the point they stay off now to help. My educated guess is that its bacterial but nothing has worked to cure it. It cant be parasitic except the behavior points to such. My last treatment was 10 days of CP (at double dose recommended) called the “wonder drug”. Expensive but Did nothing. Is there anything stronger than the meds used to kill a bad bacteria in 625g DT? Could it be fungal and if so is there a treatment I should try. Don’t think its viral like Lymph but if its another viral, what can I do as it seems to be contagious. If not I’m afraid the option will be very sad....A slow death which will lead to me to some deep thinking and getting out of the hobby as never want to go thru this again.
 
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Flame2hawk

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Anything strong enough to kill all bacteria & fungus (Ciprofloxacin, Enrofloxacin) is also going to wipe out your biofilter. Which will lead to ammonia spikes. There's no way of not killing the good bacteria with the bad sometimes.
CAn it be fungal? Recently read....

“The most common type of fungal infection in saltwater and freshwater aquarium is body fungus – this type of infection is very distinctive and generally easy to diagnose. These fungal infections typically manifest in the form of fuzzy patches growing on the body or fins of infected fish. As the infection spreads, the growths may become enlarged and could begin to take on a green or brownish tint as a result of debris particles becoming trapped on the filaments. Once this type of fungal infection sets in, it can quickly spread throughout the body of infected fish.

You might recall that the first fish infected was blue throat trigger. Before it perished it met the discritption above. Currently the queen angel meets the definition. What do you think? If you think its possible, whats bes treatment? Thx
 

Humblefish

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You might recall that the first fish infected was blue throat trigger. Before it perished it met the discritption above. Currently the queen angel meets the definition. What do you think? If you think its possible, whats bes treatment? Thx
Acriflavine and Methylene Blue are considered the best treatments for SW fungus. See links below:


 
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